Jaipreet Virdi, Mara Mills, and Sarah F. Rose introduce a disability history of science in the current volume of Osiris, which they co-edited. Across the volume, contributors trace the disabling impacts of scientific theories and practices in the contexts of war, factory labor, insurance, and colonialism; others excavate racial and settler ableism in the history of scientific facts, protocols, and collections; still others query the boundaries between scientific, lay, and disability expertise. Contending that disability alters method, the volume’s authors bring new sources and interpretation techniques to the history of science, overturn familiar narratives, apply disability analyses to established terms and archives, and discuss accessibility issues for disabled historians.